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| | 6,6-dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine Basic information |
| Product Name: | 6,6-dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine | | Synonyms: | 6,6-dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine;Methanone, (2-amino-4,5,6,7-tetrahydro-6,6-dimethylbenzo[b]thien-3-yl)(4-methylphenyl)-;GLP-1 Receptor modulator 1;GLP-1R agonist 39 | | CAS: | 1461715-47-8 | | MF: | C18H21NOS | | MW: | 299.43 | | EINECS: | | | Product Categories: | | | Mol File: | 1461715-47-8.mol |  |
| | 6,6-dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine Chemical Properties |
| Boiling point | 503.8±50.0 °C(Predicted) | | density | 1.148±0.06 g/cm3(Predicted) | | solubility | DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml | | pka | -0.86±0.40(Predicted) |
| | 6,6-dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine Usage And Synthesis |
| Uses | GLP-1 Receptor modulator 1 (Compound 7) is a potent GLP-1 receptor positive allosteric modulator. GLP-1 Receptor modulator 1 can be used for the research of obesity and type 2 diabetes[1]. | | References | [1] Campbell JA, et al. Synthesis and biological studies of 2-aminothiophene derivatives as positive allosteric modulators of glucagon-like peptide 1 receptor. Bioorg Med Chem. 2024 Sep 1;111:117864. DOI:10.1016/j.bmc.2024.117864 |
| | 6,6-dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine Preparation Products And Raw materials |
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