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| | 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Basic information |
| Product Name: | 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one | | Synonyms: | 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one;MLS000532223;2-Propyn-1-one, 1-(3-nitrophenyl)-3-phenyl-;1-(3-Nitrophenyl)-3-phenylprop-2-yn-1-one;MLS-532223;GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GTPases,Ras,inhibit;MLS000532223, 10 mM in DMSO | | CAS: | 16616-39-0 | | MF: | C15H9NO3 | | MW: | 251.24 | | EINECS: | | | Product Categories: | | | Mol File: | 16616-39-0.mol |  |
| | 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Chemical Properties |
| Melting point | 120-121 °C | | Boiling point | 419.6±47.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | RT (des.) | | solubility | Soluble in DMSO (up to 20 mg/ml). | | form | solid | | color | Beige | | Stability: | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months. |
| | 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Usage And Synthesis |
| Description | MLS-532223 (16616-39-0) is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable. | | Uses | MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 values ranging from 16 μM to 120 μM. MLS000532223 prevents GTP binding to several GTPases[1]. | | Definition | ChEBI: 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one is an aromatic compound. | | References | [1] ZURAB SURVILADZE . Identification of a Small GTPase Inhibitor Using a High-Throughput Flow Cytometry Bead-Based Multiplex Assay[J]. SLAS Discovery, 2010, 15 1: Pages 10-20. DOI:10.1177/1087057109352240 |
| | 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Preparation Products And Raw materials |
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