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(R)-N-Boc-1-Naphthylalanine

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Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:(R)-N-BOC-1-Naphthylalanine
CAS:76932-48-4
Purity:98%(min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
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Products Intro: Product Name:Boc-D-1-Nal-OH
CAS:76932-48-4
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Products Intro: Product Name:(R)-N-Boc-1-Naphthylalanine
CAS:76932-48-4
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Products Intro: Product Name:(R)-N-Boc-1-Naphthylalanine
CAS:76932-48-4
Purity:0.99 Package:5KG;1KG
Company Name: BOC Sciences
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Products Intro: Product Name:Boc-3-(1-naphthyl)-D-alanine
CAS:76932-48-4
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(R)-N-Boc-1-Naphthylalanine manufacturers
(R)-N-Boc-1-Naphthylalanine Basic information
Product Name:(R)-N-Boc-1-Naphthylalanine
Synonyms:N-ALPHA-(TERT-BUTYLOXYCARBONYL)-3-(1-NAPHTHYL)-D-ALANINE;N-ALPHA-T-BOC-BETA-(1-NAPHTHYL)-D-ALANINE;N-ALPHA-T-BUTOXYCARBONYL-3-(1-NAPHTHYL)-D-ALANINE;BOC-(R)-2-AMINO-3-(NAPHTHALEN-1-YL)PROPANOIC ACID;BOC-3-(1-NAPHTHYL)-D-ALA;BOC-3-(1-NAPHTHYL)-D-ALANINE;BOC-BETA-(1-NAPHTHYL)-D-ALANINE;BOC-D-ALA(1-NAPH)-OH
CAS:76932-48-4
MF:C18H21NO4
MW:315.36
EINECS:
Product Categories:Alanine [Ala, A];Unusual Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;Amino Acids;a-amino;Boc-Amino acid series
Mol File:76932-48-4.mol
(R)-N-Boc-1-Naphthylalanine Structure
(R)-N-Boc-1-Naphthylalanine Chemical Properties
Melting point 145-148 °C(lit.)
alpha 53 º (c=2.5 in MeOH)
Boiling point 454.92°C (rough estimate)
density 1.2164 (rough estimate)
refractive index 1.5740 (estimate)
storage temp. Sealed in dry,2-8°C
solubility DMF: 25 mg/ml
DMSO: 10 mg/ml
Ethanol: 25 mg/ml
pka3.88±0.30(Predicted)
form Solid
color White to off-white
Optical Rotation[α]22/D +53°, c = 2.5 in methanol
BRN 6180114
Major Applicationpeptide synthesis
InChI1S/C18H21NO4/c1-18(2,3)23-17(22)19-15(16(20)21)11-13-9-6-8-12-7-4-5-10-14(12)13/h4-10,15H,11H2,1-3H3,(H,19,22)(H,20,21)/t15-/m1/s1
InChIKeyKHHIGWRTNILXLL-OAHLLOKOSA-N
SMILESCC(C)(C)OC(=O)N[C@H](Cc1cccc2ccccc12)C(O)=O
CAS DataBase Reference76932-48-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 29242990
Storage Class13 - Non Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
(R)-N-Boc-1-Naphthylalanine Usage And Synthesis
Chemical Propertiesoff-white to yellowish crystalline powder
UsesBoc-D-1-Nal-OH is an antiviral.
reaction suitabilityreaction type: Boc solid-phase peptide synthesis
References[1] OLGA V. GOZHINA  Tore L  John Sigurd Svendsen. Synthesis and antimicrobial activity of α-aminoboronic-containing peptidomimetics[J]. Journal of Peptide Science, 2013, 20 1: 20-24. DOI: 10.1002/psc.2583
[2] SKYE R. DOERING. Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput “Unbiased” Screening Campaign[J]. Journal of Medicinal Chemistry, 2021, 64 9: 5577-5592. DOI: 10.1021/acs.jmedchem.0c02041
(R)-N-Boc-1-Naphthylalanine Preparation Products And Raw materials
Tag:(R)-N-Boc-1-Naphthylalanine(76932-48-4) Related Product Information
(R)-N-Boc-(4-Pyridyl)alanine (S)-N-Boc-(4-Pyridyl)alanine β-Alanine Phenprobamate D-Alanine EC 2.6.1.2 Boc-beta-alanine DL-Alanine L-Alanine 1-(1-NAPHTHYL)-2-THIOUREA DI-TERT-BUTYL ETHER D-1-Naphthylalanine BOC-D-Alanine (S)-N-BOC-1-NAPHTHYLALANINE, 95%, 98% EE,(S)-N-BOC-1-NAPHTHYLALANINE,(S)-N-BOC-1-Naphthylalanine, 98% ee (R)-N-BOC-2-NAPHTHYLALANINE, 95%, 98% EE,(S)-N-BOC-2-NAPHTHYLALANINE,(R)-N-BOC-2-Naphthylalanine, 98% ee, 95%,(R)-N-BOC-2-NAPHTHYLALANINE (S)-N-BOC-2-NAPHTHYLALANINE,(S)-N-Boc-2-naphthylalanine, 95%, ee:98%,(S)-N-BOC-2-Naphthylalanine, 98% ee, 95% (R)-N-Boc-1-Naphthylalanine