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| | Ac-VDVAD-AFC Basic information |
| Product Name: | Ac-VDVAD-AFC | | Synonyms: | AC-VAL-ASP-VAL-ALA-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;AC-VAL-ASP-VAL-ALA-ASP-AFC;CASPASE 2 (ICH-1) SUBSTRATE 1F, FLUOROGENIC;N-ACETYL-VAL-ASP-VAL-ALA-ASP-7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;BKQMJQIAIFEZJR-OIOUIRQFSA-N;3-[2-[[2-[[2-[(2-acetamido-3-methylbutanoyl)amino]-3-carboxypropanoyl]amino]-3-methylbutanoyl]amino]propanoylamino]-4-oxo-4-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]butanoic acid;L-α-Asparagine, N-acetyl-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI);(4S,7S,10S,13S,16S)-7-(carboxymethyl)-4,10-diisopropyl-13-methyl-2,5,8,11,14-pentaoxo-16-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12,15-pentaazaoctadecan-18-oic acid | | CAS: | 210344-94-8 | | MF: | C33H41F3N6O12 | | MW: | 770.71 | | EINECS: | | | Product Categories: | Caspase/Related Products;peptide | | Mol File: | Mol File |  |
| | Ac-VDVAD-AFC Chemical Properties |
| Boiling point | 1137.178±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.403±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | −20°C | | solubility | DMSO/DMF: 20 mM | | form | powder | | pka | 4.095±0.10(predicted) |
| | Ac-VDVAD-AFC Usage And Synthesis |
| Uses | Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer[1]. | | References | [1] Pan Yang, et al. Quercetin attenuates the proliferation of arsenic-related lung cancer cells via a caspase-dependent DNA damage signaling. Mol Carcinog. 2022 Jul;61(7):655-663. DOI:10.1002/mc.23408 |
| | Ac-VDVAD-AFC Preparation Products And Raw materials |
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