- CAPS
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- $0.00 / 25Kg/Drum
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2026-01-30
- CAS:1135-40-6
- Min. Order: 1KG
- Purity: 99%min
- Supply Ability: 500kgs
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| | 3-Cyclohexylaminopropanesulfonic Acid Basic information |
| | 3-Cyclohexylaminopropanesulfonic Acid Chemical Properties |
| Melting point | >300 °C(lit.) | | bulk density | 400kg/m3 | | density | 1.1809 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | 1.5250 (estimate) | | Fp | >110℃ | | storage temp. | room temp | | solubility | H2O: 0.5 M at 20 °C, clear | | form | Powder/Solid | | color | White | | Odor | Odorless | | PH | 3.0-7.0 (20℃, 0.5M in H2O) | | PH Range | 3 - 7 | | pka | 10.4(at 25℃) | | Water Solubility | 9 g/100 mL (20 ºC) | | λmax | λ: 260 nm Amax: ≤0.04
λ: 280 nm Amax: ≤0.04 | | Merck | 14,1767 | | BRN | 2835588 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChI | 1S/C9H19NO3S/c11-14(12,13)8-4-7-10-9-5-2-1-3-6-9/h9-10H,1-8H2,(H,11,12,13) | | InChIKey | PJWWRFATQTVXHA-UHFFFAOYSA-N | | SMILES | OS(=O)(=O)CCCNC1CCCCC1 | | LogP | 0.3 at 25℃ | | CAS DataBase Reference | 1135-40-6(CAS DataBase Reference) | | EPA Substance Registry System | 1-Propanesulfonic acid, 3-(cyclohexylamino)- (1135-40-6) | | Absorption | ≤0.2 at 260 in H2O at 0.5M
≤0.2 at 280 in H2O at 0.5M |
| | 3-Cyclohexylaminopropanesulfonic Acid Usage And Synthesis |
| Chemical Properties | White/clear crystalline powder | | Uses | 3-Cyclohexylaminopropanesulfonic Acid buffer salt is used to formulate CAPS buffer, a zwitterionic buffer that is useful in the range of pH 7.9-11.1. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. Used in the electrotransfer of proteins to PVDF (sc-3723) or nitrocellulose membranes (sc-3718, sc-3724). The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS is not one of the original Good's buffers, although it has a similar structure to the other propanesulfonic acids and was selected as a highly water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins, minimal salt effects. It is a biological buffer.
| | Description | 3-Cyclohexylaminopropanesulfonic Acid, also known as 3-(Cyclohexylamino)-1-propanesulfonic acid (CHAPS) or N-Cyclohexyl-3-aminopropanesulfonic acid, is a detergent with a high affinity for basic proteins that can be used to extract these proteins from biological samples and solubilize them. CHAPS is a type of ampholyte, which means it has both anionic and cationic groups. | | Definition | ChEBI: Cyclohexylaminopropanesulfonic acid is an amine. | | Flammability and Explosibility | Not classified | | References |
[1] David A. Paulls, A. Townshend. “Sensitized determination of sulfite using flow injection with chemiluminescent detection.” Analyst 6 1 (1995): 467–469.
[2] Takashi Yoshitake. “Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine.” Analytical biochemistry 312 2 (2003): 125–33.
[3] Keiichi Fujimori. “Determination of Sulfide with Acidic Permanganate Chemiluminescence for Development of Deep-sea in-situ Analyzers.” Analytical Sciences 27 2 (2011): 183–186.
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| | 3-Cyclohexylaminopropanesulfonic Acid Preparation Products And Raw materials |
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