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5-AMINOVALERIC ACID

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CAS:660-88-8
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CAS:660-88-8
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5-AMINOVALERIC ACID Basic information
Product Name:5-AMINOVALERIC ACID
Synonyms:5-Aminovaleric acid≥ 98% (HPLC);5-Ava-OH;H2N(CH2)4COOH;5-AMinovaleric acid, 97% 5GR;Pentanoic acid, 5-amino-;Valeric acid, 5-amino-;DELTA-AMINOVALERIC ACID;DELTA-AMINO-N-VALERIC ACID
CAS:660-88-8
MF:C5H11NO2
MW:117.15
EINECS:211-544-5
Product Categories:omega-Aminocarboxylic Acids;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Amino Acids and Derivatives;Miscellaneous
Mol File:660-88-8.mol
5-AMINOVALERIC ACID Structure
5-AMINOVALERIC ACID Chemical Properties
Melting point 158-161 °C(lit.)
Boiling point 247.5±23.0 °C(Predicted)
density 1.2000 (estimate)
refractive index 1.4650 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
pka4.27(at 25℃)
form Crystalline Powder
color White to off-white
BRN 906833
Major Applicationpeptide synthesis
InChIInChI=1S/C5H11NO2/c6-4-2-1-3-5(7)8/h1-4,6H2,(H,7,8)
InChIKeyJJMDCOVWQOJGCB-UHFFFAOYSA-N
SMILESC(O)(=O)CCCCN
CAS DataBase Reference660-88-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
HS Code 29224999
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
5-AMINOVALERIC ACID Usage And Synthesis
Chemical Propertieswhite to off-white crystalline powder
Uses5-Aminovaleric Acid is used in the development of drugs that halts severe type of seizures.
Uses5-Aminovaleric acid (5-AVA) is used:
  • In the preparation of (5-AVA)x(MA)1-xPbI3, a perovskite for fabricating printable mesoscopic perovskite solar cell.
  • As a spacer in the synthesis of rhenium and technetium-99m labeled insulin.
  • To synthesize dipeptides that self-assemble to form nanotubes in the solid state as well as in solution over a wide range of pH.
  • As a starting material in the total synthesis of an alkaloid, lycoposerramine Z.

DefinitionChEBI: A delta-amino acid comprising pentanoic acid with an amino substituent at C-5; a methylene homologue of gamma-aminobutyric acid (GABA) that is a weak GABA agonist.
reaction suitabilityreaction type: solution phase peptide synthesis
Purification MethodsCrystallise it from H2O/EtOH. When heated above its melting point, it is converted to 2-piperidone with m 200o. [Wood & Colver J Am Chem Soc 67 654 1945, Beilstein 4 IV 2636.]
Tag:5-AMINOVALERIC ACID(660-88-8) Related Product Information
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