1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE manufacturers
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| | 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Basic information |
| Product Name: | 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE | | Synonyms: | {[(3-Chloroanilino)(imino)methyl]amino}methanimidamide hydrochloride, N-(3-Chlorophenyl)imidodicarbonimidic diamide hydrochloride;2-(3-chlorophenyl)-1-(diaminomethylidene)guanidine,hydrochloride;1-(m-chlorophenyl)-biguanidmonohydrochloride;n-(3-chlorophenyl)-imidodicarbonimidicdiamidemonohydrochloride;N-(3-CHLOROPHENYL)IMIDODICARBONIMIDIC DIAMIDE HYDROCHLORIDE;1-(M-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE;1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE;M-CPBG HYDROCHLORIDE | | CAS: | 2113-05-5 | | MF: | C8H11Cl2N5 | | MW: | 248.11 | | EINECS: | | | Product Categories: | Serotonin receptor | | Mol File: | 2113-05-5.mol |  |
| | 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Chemical Properties |
| Melting point | 190-194 °C(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | H2O: soluble | | form | solid | | color | white | | Water Solubility | Soluble to 100 mM in water | | Sensitive | Hygroscopic | | CAS DataBase Reference | 2113-05-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | DU1780000 | | HS Code | 2925290090 |
| | 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Usage And Synthesis |
| Uses | Specific agonist for 5-HT receptor | | Biological Activity | Prototypical potent and selective 5-HT 3 receptor agonist. | | in vivo | m-CPBG hydrochloride (80 and 160 nM) significantly reduces water intake elicited by an acute salt load[1].
m-CPBG hydrochloride (third ventricle injection; 160 nM) significantly inhibits water intake in hypovolemic animals[1].
m-CPBG hydrochloride (third ventricle injection; 320 nM) decreases water intake in water-deprived rats[1].
m-CPBG hydrochloride (central administration) inhibits water intake induced by pharmacological activation of central cholinergic and angiotensinergic pathways[1]. | Animal Model: | Wistar male rats[1] | | Dosage: | 80, 160 and 320 nM | | Administration: | Ventricle injection | | Result: | Decreased water intake induced by water deprivation, acute salt load and hypovolemia. |
| | storage | Desiccate at RT |
| | 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE Preparation Products And Raw materials |
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