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| | 5H-Pyrido[4,3-b]indole-7-propanoic acid Basic information |
| | 5H-Pyrido[4,3-b]indole-7-propanoic acid Chemical Properties |
| Boiling point | 529.5±35.0 °C(Predicted) | | density | 1.387±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light | | form | Solid | | pka | 4.49±0.10(Predicted) | | color | White to off-white |
| | 5H-Pyrido[4,3-b]indole-7-propanoic acid Usage And Synthesis |
| Uses | Aberrant tau ligand 1 is a ligand for tau proteins with abnormal forms. Aberrant tau ligand 1 can be used for synthesis of PROTAC aberrant Tau degrader QC-01-175 (HY-134850)[1]. | | References | [1] Silva MC, et al., Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. Elife. 2019 Mar 25;8:e45457. DOI:10.7554/eLife.45457 |
| | 5H-Pyrido[4,3-b]indole-7-propanoic acid Preparation Products And Raw materials |
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