7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-

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7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Suppliers list
Company Name: Shanghai Kewel Chemical Co., Ltd.  
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Company Name: Hubei Yangxin Medical Technology Co., Ltd.  
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Company Name: Tianjin shijia biomedical technology co., LTD  
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Company Name: Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.  
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Company Name: Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd  
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7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Basic information
Product Name:7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-
Synonyms:Tofacitinib N-Oxopropanenitrile;Tofacitinib N-Oxopropanenitrile. 7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-;7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-
CAS:2459302-77-1
MF:C19H21N7O2
MW:379.42
EINECS:
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Mol File:2459302-77-1.mol
7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Structure
7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Chemical Properties
Boiling point 643.8±55.0 °C(Predicted)
density 1.35±0.1 g/cm3(Predicted)
pka-2.61±0.10(Predicted)
Safety Information
MSDS Information
7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Usage And Synthesis
UsesTofacitinib N-Oxopropanenitrile is an impurity of Tofacitinib(C781351); a Janus kinase inhibitor for treatment of rheumatoid arthritis.
7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo- Preparation Products And Raw materials
Tag:7H-Pyrrolo[2,3-d]pyrimidine-7-propanenitrile, 4-[[(3R,4R)-1-(2-cyanoacetyl)-4-methyl-3-piperidinyl]methylamino]-β-oxo-(2459302-77-1) Related Product Information
2-Pentenoic acid, 3-amino-2-cyano-5-[(3R,4R)-4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-5-oxo-, ethyl ester 2-Pentenoic acid, 3-amino-2-cyano-5-[(3R,4R)-4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-5-oxo-, butyl ester Tofacitinib