| Company Name: |
TargetMol
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| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
| Products Intro: |
Product Name:TPNA10168
CAS:957942-34-6
Package:2mg/RMB 135;5mg/RMB 198;10mg/RMB 297
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| Company Name: |
1Pluschem LLC
|
| Tel: |
(858)215-1656 |
| Email: |
sales@1pchem.com |
| Products Intro: |
CAS:957942-34-6
|
| Company Name: |
A2B Chem LLC
|
| Tel: |
010 |
| Email: |
sales@a2bchem.com |
| Products Intro: |
Product Name:1-chloro-3-(methylsulfinyl)-4,5,6,7-tetrahydrobenzo[c]thiophen-4-one
CAS:957942-34-6
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| | 1-chloro-3-(methylsulfinyl)-4,5,6,7-tetrahydrobenzo[c]thiophen-4-one Basic information |
| | 1-chloro-3-(methylsulfinyl)-4,5,6,7-tetrahydrobenzo[c]thiophen-4-one Chemical Properties |
| Boiling point | 490.3±45.0 °C(Predicted) | | density | 1.54±0.1 g/cm3(Predicted) |
| | 1-chloro-3-(methylsulfinyl)-4,5,6,7-tetrahydrobenzo[c]thiophen-4-one Usage And Synthesis |
| Uses | TPNA10168 is an Nrf-2 activator that activates the Keap1-Nrf2-ARE pathway. TPNA10168 is neuroprotective against oxidative stress-induced damage. TPNA10168 significantly reduces the transcription of inflammatory genes, including TNF-α, IL-1β, IL-6, and iNOS. TPNA10168 can be used in research on anti-inflammatory and neurological diseases[1]. | | Definition | ChEBI: 1-Chloro-3-(methylsulfinyl)-4,5,6,7-tetrahydrobenzo[c]thiophen-4-one is an aromatic ketone. | | References | [1] Izumi Y, et al. TPNA10168, an Nrf-2 activator, attenuates inflammatory responses independently of Nrf2 in microglial BV-2 cells: Involvement of the extracellular-signal-regulated kinase pathway. J Pharmacol Sci. 2022 May;149(1):1-10. DOI:10.1016/j.jphs.2022.02.004 |
| | 1-chloro-3-(methylsulfinyl)-4,5,6,7-tetrahydrobenzo[c]thiophen-4-one Preparation Products And Raw materials |
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