Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide

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Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide manufacturers

  • A110
  • A110 pictures
  • $1980.00
  • 2026-04-21
  • CAS:1185388-35-5
  • Purity:
  • Supply Ability: 10g
Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Basic information
Product Name:Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide
Synonyms:Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide
CAS:1185388-35-5
MF:C19H15ClN4O2
MW:366.8
EINECS:
Product Categories:
Mol File:1185388-35-5.mol
Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Structure
Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Chemical Properties
Melting point 172-174 °C
Boiling point 588.0±60.0 °C(Predicted)
density 1.37±0.1 g/cm3(Predicted)
pka2.32±0.10(Predicted)
Safety Information
MSDS Information
Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Usage And Synthesis
DescriptionA110 is a potent and selective inhibitor of IMPDHs. A110 binds to the NAD(+) cofactor site and forms a ternary complex with IMP.
UsesA110 is the inhibitor for Cryptosporidium parvum inosine monophosphate dehydrogenase (CpIMPDH). A110 inhibits CpIMPDH in Toxoplasma gondii with IC50 of 18 nM. A110 exhibits pro-parasitic efficacy and cause parasitemia[1].
References[1] Gorla SK, et al., Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis. Antimicrob Agents Chemother. 2014;58(3):1603-14. DOI:10.1128/AAC.02075-13
Quinoline, 4-[(1R)-1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl]ethoxy]-, 1-oxide Preparation Products And Raw materials
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