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| | 5,8,11-Tridecatrienoic acid, 13-[(2S,3R)-3-pentyloxiranyl]-, methyl ester, (5Z,8Z,11Z)- (9CI) Basic information |
| Product Name: | 5,8,11-Tridecatrienoic acid, 13-[(2S,3R)-3-pentyloxiranyl]-, methyl ester, (5Z,8Z,11Z)- (9CI) | | Synonyms: | 5,8,11-Tridecatrienoic acid, 13-[(2S,3R)-3-pentyloxiranyl]-, methyl ester, (5Z,8Z,11Z)- (9CI);14S(15R)-EET methyl ester | | CAS: | 110901-52-5 | | MF: | C21H34O3 | | MW: | 334.49 | | EINECS: | | | Product Categories: | | | Mol File: | 110901-52-5.mol | ![5,8,11-Tridecatrienoic acid, 13-[(2S,3R)-3-pentyloxiranyl]-, methyl ester, (5Z,8Z,11Z)- (9CI) Structure](CAS/20210305/GIF/110901-52-5.gif) |
| | 5,8,11-Tridecatrienoic acid, 13-[(2S,3R)-3-pentyloxiranyl]-, methyl ester, (5Z,8Z,11Z)- (9CI) Chemical Properties |
| Boiling point | 425.8±45.0 °C(Predicted) | | density | 0.952±0.06 g/cm3(Predicted) | | solubility | Ethanol: Soluble |
| | 5,8,11-Tridecatrienoic acid, 13-[(2S,3R)-3-pentyloxiranyl]-, methyl ester, (5Z,8Z,11Z)- (9CI) Usage And Synthesis |
| Uses | 14S(15R)-EET methyl ester is an oxylipin and a cytochrome P450 metabolite of Arachidonic acid (HY-109590). | | References | [1] F A Fitzpatrick, et al. Inhibition of cyclooxygenase activity and platelet aggregation by epoxyeicosatrienoic acids. Influence of stereochemistry. J Biol Chem. 1986 Nov 15;261(32):15334-8. PMID:3095326 [2] B E DAIKH. Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9.[J]. Journal of Pharmacology and Experimental Therapeutics, 1994, 271 3: 1427-1433. [3] PATRICK Y.-K WONG J. R F Pi Shiang Lai. Mechanism and signal transduction of 14 (R), 15 (S)-epoxyeicosatrienoic acid (14,15-EET) binding in guinea pig monocytes[J]. Prostaglandins & other lipid mediators, 2000, 62 4: Pages 321-333. DOI: 10.1016/s0090-6980(00)00079-4 [4] YONGDE ZHANG. EET homologs potently dilate coronary microvessels and activate BK(Ca) channels.[J]. American journal of physiology. Heart and circulatory physiology, 2001, 280 6 1: H2430-40. DOI: 10.1152/ajpheart.2001.280.6.h2430 |
| | 5,8,11-Tridecatrienoic acid, 13-[(2S,3R)-3-pentyloxiranyl]-, methyl ester, (5Z,8Z,11Z)- (9CI) Preparation Products And Raw materials |
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