5-Aminosalicylic Acid NEW
| Price | $45 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-31 |
Product Details
| Product Name: 5-Aminosalicylic Acid | CAS No.: 89-57-6 |
| Purity: 99.98% | Supply Ability: 10g |
| Release date: 2025/10/31 |
Product Introduction
Bioactivity
| Name | 5-Aminosalicylic Acid |
| Description | 5-Aminosalicylic Acid (5-ASA) is a specific PPARγ agonist and also inhibits P21-activated kinase 1(PAK1) and NF-Κb. 5-Aminosalicylic Acid has anti-cancer and anti-inflammatory activities. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN). |
| In vitro | METHODS: HEK293 cells carrying the pendrin P123S mutant were treated with 5-Aminosalicylic Acid for 72 hours, and cytotoxicity was detected by the MTT method. RESULTS: The IC50 of 5-Aminosalicylic Acid on HEK293 cells carrying the pendrin P123S mutant was >15 mM. [1] |
| In vivo | METHODS: To study the anti-tumor activity of 5-Aminosalicylic Acid, 5-Aminosalicylic Acid (50 mM) was administered to SCID mice inoculated with HT-29 colon cancer cells for 21 consecutive days. RESULTS: The tumor weight and volume of SCID mice treated with 5-Aminosalicylic acid were reduced by 80-86%. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 29 mg/mL (189.37 mM), Sonication is recommended. DMSO : 80 mg/mL (522.4 mM), Sonication is recommended. |
| Keywords | PPARγ | PPAR | Peroxisome proliferator-activated receptors | PAK | p21 activated kinases | Nuclear factor-κB | Nuclear factor-kappaB | NF-κB | NFκB | NF-kB | NFkB | MPO | Inhibitor | inhibit | GlutathionePeroxidase | Glutathione Peroxidase | EndogenousMetabolite | Endogenous Metabolite | COX | ALOX5 | 5-Aminosalicylic Acid | 5Aminosalicylic Acid | 5 Aminosalicylic Acid |
| Inhibitors Related | Sucrose | Acetaminophen | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | L-Methionine | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Pain-Related Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Natural Product Library for HTS | FDA-Approved Drug Library | FDA-Approved Kinase Inhibitor Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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