Allopregnanolone

‌Product Overview‌
Allopregnanolone (CAS: 516-54-1), a neuroactive steroid, is a potent endogenous modulator of GABA_A receptors. It regulates neuronal excitability and stress responses, making it critical for treating neurological disorders like postpartum depression and epilepsy. This white crystalline powder also serves as a key ingredient in anti-aging cosmetics and pharmaceutical research intermediates.

✨ ‌Key Advantages‌
✅ ‌High Purity‌: ≥99% purity (HPLC/GC tested) for pharmaceutical and research applications.
✅ ‌Neuroprotective Activity‌: Demonstrates EC₅₀ values of 10-50 nM in GABA_A receptor modulation.
✅ ‌Thermal Stability‌: Melting point 176-178°C ensures stability during formulation and storage.

🔬 ‌Application Fields‌

• ‌Pharmaceuticals‌: Core component in treatments for postpartum depression, epilepsy, and neurodegenerative diseases.

• ‌Cosmetics‌: Enhances anti-aging formulations by promoting cellular repair and skin resilience.

• ‌Research‌: Vital for neurosteroid studies and drug development targeting GABA pathways.

📜 ‌Quality Assurance‌

• Produced in ‌GMP-certified facilities‌ with compliance to EP/USP standards.

• Rigorous quality control via ‌HPLC, NMR, and mass spectrometry‌ for batch consistency.

• Complies with ‌MSDS safety guidelines‌ for safe handling and storage.

📈 ‌Market Insights‌
The global neurosteroid market is projected to grow at a ‌CAGR of 7.8% (2025-2030)‌, driven by rising demand for non-hormonal antidepressants and neurological therapies. Allopregnanolone’s role in the ‌$1.2B postpartum depression treatment market‌ underscores its commercial significance.