Idoxuridine hydrate NEW
| Price | $2140 | $2785 | $3520 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: Idoxuridine hydrate | CAS No.: 17140-71-5 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | Idoxuridine hydrate |
| Description | Idoxuridine hydrate (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is a competitive inhibitor of phosphorylases. As an iodinated thymidine analogue, it effectively inhibits DNA polymerase and hinders viral replication, making it useful in the treatment of viral eye infections such as herpes simplex keratitis. Against feline herpesvirus, Idoxuridine has been found to have an IC50 value of 4.3 μM [1]. |
| In vitro | Idoxuridine hydrate, at concentrations ranging between 2-10 μM over a 72-hour period, exhibits an antiviral IC50 value of 4.3 μM, as demonstrated in a Cell Proliferation Assay on Crandell-Reese feline kidney (CRFK) cells. Additionally, a Cell Cytotoxicity Assay revealed that exposure to concentrations of 5-50 μM for the same duration resulted in a relative reduction of 10.8% in CRFK cell viability. |
| In vivo | Idoxuridine hydrate, administered through intraperitoneal injection at a dosage of 50-200 mg/kg for three times at three-hour intervals, has been shown to enhance the production of hemolysin plaque-forming cells (HPFC) against sheep red blood cells (SRBC) in both female and male C3HeB/FeJ mice as well as A/J male mice. This effect was observed across the specified dosage range. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | PTP1B-IN-22 | Ellagic acid | β-Glycerophosphate disodium salt pentahydrate | L-Ascorbic acid 2-phosphate trisodium | Idoxuridine | Tartaric acid disodium dihydrate | Cyclosporine | Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride | Stearic acid | CaMKP Inhibitor | Cyclosporin A | β-Glycerophosphate disodium salt hydrate |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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