Mal-Pc NEW
| Price | Get Latest Price | |
| Package | 5mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: Mal-Pc | CAS No.: 2670367-74-3 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | Mal-Pc |
| Description | Mal-Pc, a phthalocyanine-based molecular photosensitizer featuring maleimides, interacts with GSH to diminish its levels and decrease aggregation, enhancing the ROS (Reactive Oxygen Species)-dependent efficacy of photodynamic therapy (PDT) in targeting cancer cells [1]. |
| In vitro | Mal-Pc, featuring two axial maleimide substituents, accelerates accumulation in cancer cells, enabling a reaction with GSH which leads to GSH depletion and reduced aggregation. This enhances the ROS-mediated anticancer efficacy of PDT [1]. Fluorescence imaging revealed that Mal-Pc is rapidly cleared from normal cells, attributed to the formation of a highly hydrophilic reaction product [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | ReactiveOxygenSpecies | Reactive Oxygen Species |
| Inhibitors Related | Cysteamine hydrochloride | Imeglimin hydrochloride | Acetylcysteine | L-Ascorbic acid | Hesperidin | Glucosamine | D-(+)-Glucono-1,5-lactone | 3-Indolepropionic acid | L-Ascorbic acid sodium salt | Sodium 2-oxopropanoate | Naringenin | Uric Acid |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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