MIRA-1 NEW
| Price | $33 | $51 | $103 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: MIRA-1 | CAS No.: 72835-26-8 |
| Purity: 99.38% | Supply Ability: 10g |
| Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | MIRA-1 |
| Description | MIRA-1 (WRN Helicase Inhibitor) is a restorer of wild-type p53 conformation/cellular function and selectively inhibits Werner syndrome WRN helicase activity with an IC50 of 20 µM. |
| In vitro | MIRA-1 induces p53 transcriptional transactivation of p21, MDM2, and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent manner in vitro with an IC50 of 10μM[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (10.92 mM), Sonication is recommended. DMSO : 20 mg/mL (109.19 mM), Sonication is recommended. Ethanol : 20 mg/mL (109.19 mM), Sonication is recommended. |
| Keywords | WRN helicase | SKOV | Saos-2 | RNASynthesis | RNA Synthesis | p53 | NSC-19630 | NSC19630 | MIRA-1 | MIRA1 | MIRA 1 | MDM-2/p53 | Inhibitor | inhibit | H1299 | DNASynthesis | DNA Synthesis | Apoptosis | Anticancer |
| Inhibitors Related | Stavudine | Cysteamine hydrochloride | Sodium 4-phenylbutyrate | Metronidazole | Guanidine hydrochloride | Citric Acid Triammonium | Tributyrin | Adenine | Cystamine dihydrochloride | Thymidine | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
| Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Anti-Lung Cancer Compound Library | DNA Damage & Repair Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $2.00/100kg |
VIP1Y
|
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
|
2025-06-23 | |
| $999.00/5g |
VIP2Y
|
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
|
2024-08-09 | |
| $/ |
VIP5Y
|
RongNa Biotechnology Co.,Ltd
|
2025-04-29 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY