Product Details
| Product Name:
Neophytadiene |
CAS No.:
504-96-1 |
| Supply Ability:
10g |
Release date:
2025/11/08 |
Product Introduction
Bioactivity
| Name | Neophytadiene |
| Description | Neophytadiene is a diterpene compound extracted from Turbinaria ornate, with anti-inflammatory, antidepressant, anxiolytic-like, anticonvulsant, antioxidant, and cardioprotective effects. It inhibits LPS-induced inflammation in RAW 264.7 macrophages and Sprague-Dawley rats and can be used in neurological disease research. |
| In vitro | Neophytadiene has an IC50 value of 50 μM for RAW 264.7 cells.
Neophytadiene (25, 50, and 100 μM) pretreated LPS-induced RAW 264.7 cells to inhibit NO production and down-regulate the production of inducable nitric oxide synthase (iNOS).
Neophytadiene (25, 50, and 100 μM) significantly reduced the production of TNF-α and NF-κB proteins in LPS-induced cells. [1] |
| In vivo | Neophytadiene (12, 25, and 50 mg/kg, orally administered once daily for 7 days) showed that Neophytadiene improved CKMB levels in LPS treated rats in a dose-dependent manner. Restores SOD and catalase activity and reduces levels of pro-inflammatory cytokines such as IL1β, IL6 and IL10. [1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 5 mg/mL (17.95 mM), Sonication is recommended.
|
| Keywords | Neophytadiene |
| Inhibitors Related | Thiamine monochloride | Butylated hydroxytoluene | Methyl 3,4-dihydroxybenzoate | AFMK | Propyl gallate | L-Tartaric acid | Neohesperidin | Sulbutiamine | m-Coumaric acid | L-Cystine | 3-Indolepropionic acid | Trolox |
| Related Compound Libraries | Traditional Chinese Medicine Monomer Library | Chinese Pharmacopoeia Natural Product Library | Natural Product Library for HTS |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States