N,N-Dimethylsphingosine NEW
| Price | $253 | $475 | $1080 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-11 |
Product Details
| Product Name: N,N-Dimethylsphingosine | CAS No.: 119567-63-4 |
| Supply Ability: 10g | Release date: 2025/09/11 |
Product Introduction
Bioactivity
| Name | N,N-Dimethylsphingosine |
| Description | N,N-Dimethylsphingosine, an endogenous metabolite, is a potent competitive sphingosine kinase (SphK) inhibitor that selectively inhibits sphingosine phosphorylation without affecting its N-acylation.DMS is elevated in models of neuropathic pain, and may mediate mechanical nociception by increasing the release of IL-1β and MCP-1. |
| In vitro | Methods: RAW264.7 cells were treated with N,N-Dimethylsphingosine (0-5μM, 24 hours), and cell viability was determined by MTT assay. Results: N,N-Dimethylsphingosine can inhibit the growth of RAW264.7 cells with an IC50 value of 2.3μM. [1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 20 mg/mL (61.06 mM), Sonication is recommended. DMSO : 5 mg/mL (15.26 mM), Sonication is recommended. |
| Keywords | N,N-Dimethylsphingosine | N,NDimethylsphingosine | N,N Dimethylsphingosine |
| Inhibitors Related | Fingolimod hydrochloride | SLP9101555 | LX-2931 | Sphingosine-1-phosphate | CYM50374 | K145 hydrochloride | ASP-4058 | Ceranib-2 | Siponimod | Fingolimod | MP-A08 | Ozanimod |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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