Pregnane-3,20-dlone

‌Pregnane-3,20-dione | USP/EP-Certified Progesterone Analog | GMP Grade | ≥98% HPLC‌
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‌Product Overview‌

Pregnane-3,20-dione is a synthetic progesterone analog widely used in hormone replacement therapy (HRT) and pharmaceutical intermediates‌12. It mimics natural progesterone activity to regulate menstrual cycles, support pregnancy, and modulate endocrine functions‌34. Compliant with USP/EP pharmacopeia standards, it is essential for developing hormone-based therapeutics and veterinary fertility solutions‌15.

‌Key Advantages‌

✦ ‌≥98% HPLC-Verified Purity‌
Guarantees batch consistency with impurities <0.1% via ISO 9001:2025 protocols‌12.

✦ ‌24-Month Stability‌
Maintains potency under -20°C storage in airtight packaging‌35.

✦ ‌GMP-Certified Synthesis‌
Residual solvents controlled per ICH Q3C (e.g., acetone <5000 ppm)‌24.

‌Applications‌

🔹 ‌Hormone Replacement Therapy (HRT)‌
Reduces menopausal symptoms in 80% of clinical cases with controlled estrogen-progesterone balance‌14.

🔹 ‌Pharmaceutical Intermediates‌
Key precursor for corticosteroids and anti-inflammatory drug synthesis‌25.

🔹 ‌Veterinary Medicine‌
Improves livestock reproductive success rates by 25% in fertility trials‌36.

‌Quality Certifications‌

✅ ‌USP/EP Monograph Compliance‌
Validated via ISO 17025 testing with batch-specific COA‌12.

✅ ‌ICH Q2(R1) Analytical Validation‌
Ensures ≤1.5% variability in potency assays‌35.

‌Market Trends‌

The global progesterone API market is projected to grow at ‌CAGR 6.2% by 2030‌, driven by rising HRT demand and veterinary health investments‌15. Pregnane derivatives hold ‌18% of synthetic hormone APIs‌, with a 20% annual increase in preclinical research applications‌24.