RTI-13951-33 NEW

Price	$1820	$2380	$3100
Package	25mg	50mg	100mg

Min. Order:
Supply Ability:	10g
Update Time:	2025-10-27

Product Details

Product Name: RTI-13951-33	CAS No.: 2244884-08-8
Supply Ability: 10g	Release date: 2025/10/27

Product Introduction

Bioactivity

Name	RTI-13951-33
Description	RTI-13951-33 is an effective and brain-penetrant GPR88 agonist (EC50: 25 nM, in GPR88 cAMP functional assay).
In vitro	RTI-13951-33 poorly inhibits SERT (IC50: 25.1 ± 2.7 μM). RTI-13951-33 elevates [35S]-GTPγS binding (EC50: 535 nM) in mouse striatal membranes but not in membranes from GPR88 KO mice. RTI-13951-33 has weak affinities at kappa opioid receptor (KOR; Ki, 2.29 μM), vesicular monoamine transporter (VMAT; Ki, 4.23 μM), and moderate affinity at serotonin transporter (SERT; Ki, 0.75 μM) [1].
In vivo	RTI-13951-33 (10 and 20 mg/kg, i.p.) dose-dependently reduces alcohol lever responses in a rat model of alcohol self-administration. RTI-13951-33 (10 mg/kg, i.p.) has sufficient brain penetration, with t1/2 of 48 min and 87 min in rat plasma and brain [1].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Keywords	RTI-13951-33 \| RTI1395133 \| RTI 13951 33 \| GPR88
Inhibitors Related	Vincamine \| Monomethyl fumarate \| Questiomycin A \| Azathioprine \| CRTh2 antagonist 2 \| Fezagepras sodium \| Benzyl nicotinate \| 1-methoxycyclopropanecarboxylic acid \| TUG-1375 \| CAY10595 \| Timapiprant \| NF-56-EJ40

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

Recommended supplier

Product name	Price		Suppliers	Update time
RTI-113	$40.00/1kg		Hebei Yanxi Chemical Co., Ltd.	2023-09-20
Polyquaternium-33	$/	VIP5Y	RongNa Biotechnology Co.,Ltd	2025-04-29
RTI-13951-33	$2380.00/50mg	VIP4Y	TargetMol Chemicals Inc.	2025-08-21

TargetMol Chemicals Inc.

2YR

United States

Since: 2011-01-07
Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA

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