| Product Identification | Back to Contents | 【Product Name】
4-Hydroxybenzoic acid methyl ester | 【Synonyms】
4-Hydroxybenzoic acid methyl ester
Maseptol
Methyl 4-hydroxybenzoate
Methyl Butex
Methyl p-hydroxybenzoate
Preserval | 【CAS】
99-76-3 | 【Formula】
C8H8O3 | 【Molecular Weight】
152.15 | 【EINECS】
202-785-7 | 【RTECS】
DH2450000 | 【RTECS Class】
Drug; Mutagen | 【Merck】
12,6182 | 【Beilstein/Gmelin】
509801 | 【Beilstein Reference】
4-10-00-00360 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Solid. | 【Solubility in water】
Slightly soluble | 【Melting Point】
125 - 128 | 【Boiling Point】
270 - 280 | 【Density】
1.1208 g/cm3 (137 C) | 【pKa/pKb】
8.30 (pKa) | 【Partition Coefficient】
1.96 | 【Heat Of Vaporization】
77.10 kJ/mol | 【Heat Of Combustion】
-3751 kJ/mol | 【Usage】
Inhibitor of growth of molds & to lesser extent bacteria, as vehicle for ophthalmic soln., Preservative. | 【Refractive Index】
1.5204 (137 C) |
| First Aid Measures | Back to Contents | 【Ingestion】
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration. | 【Skin】
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | 【Eyes】
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. |
| Handling and Storage | Back to Contents | 【Storage】
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed. | 【Handling】
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. |
| Hazards Identification | Back to Contents | 【Inhalation】
May cause respiratory tract irritation. | 【Skin】
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. | 【Eyes】
May cause moderate eye irritation. | 【Ingestion】
May cause irritation of the digestive tract. | 【Hazards】
Dusts at sufficient concentrations can form explosive mixtures with air. | 【EC Risk Phrase】
R 36/37/38 | 【EC Safety Phrase】
S 26 36 | 【UN (DOT)】
2769 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. | 【Exposure Effects】
Repeated exposure may cause sensitization dermatitis. | 【Poison Class】
5 |
| Fire Fighting Measures | Back to Contents | 【Autoignition】
> 600 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use water spray, dry chemical, or carbon dioxide. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. |
| Stability and Reactivity | Back to Contents | 【Stability】
Stable under normal temperatures and pressures. | 【Incompatibilities】
Strong oxidizing agents, strong bases. | 【Decomposition】
Carbon monoxide, carbon dioxide, acrid smoke and fumes. |
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