21-Desoxybetamethasone(382-67-2)

Contents

Product Identification	Back to Contents
【Product Name】 21-Desoxybetamethasone
【Synonyms】 9-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione
【CAS】 382-67-2
【Formula】 C22H29FO4
【Molecular Weight】 376.47
【EINECS】 206-845-3
【RTECS】 TU3834000
【RTECS Class】 Reproductive Effector; Hormone
【Merck】 12,2975
【Beilstein/Gmelin】 2228097
【Beilstein Reference】 6-08

Physical and Chemical Properties	Back to Contents
【Solubility in water】 Insoluble
【Melting Point】 217
【Vapor Pressure】 2E-13 (25 C)
【pKa/pKb】 12.80 (pKa)
【Heat Of Vaporization】 92.9 kJ/mol
【Usage】 A topical steroid used to treat inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis.

First Aid Measures	Back to Contents
【Ingestion】 If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】 If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】 In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】 In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Hazards Identification	Back to Contents
【Inhalation】 Material is irritating to mucous membranes and upper respiratory tract.
【EC Risk Phrase】 20/21/22 36/37/38 40 43
【EC Safety Phrase】 22 26 36

Exposure Controls/Personal Protection	Back to Contents
【Personal Protection】 Compatible chemical-resistant gloves. Chemical safety goggles.
【Respirators】 Government approved respirator.
【Exposure Effects】 Harmful. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect. May cause sensitization by skin contact. Target organ(s): Pituitary. Poss

Fire Fighting Measures	Back to Contents
【Flash Point】 276
【Fire Fighting】 Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures	Back to Contents
【Small spills/leaks】 Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity	Back to Contents
【Stability】 Stable at normal temperatures and pressures.
【Decomposition】 Carbon monoxide, Carbon dioxide, Hydrogen fluoride.

Company Name:	GUANGZHOU TOPWORK CHEMISTRY CO.,LTD.
Tel:	020-87317062 13048089691
Fax:
WebSite:	www.topworkchem.com/

Company Name:	Chemsky（shanghai）International Co.,Ltd.
Tel:	021-50135380
Fax:
WebSite:	www.shchemsky.com

Company Name:	China Langchem Inc.
Tel:	0086-21-58956006
Fax:	0086-21-58956100
WebSite:	www.chemicalbook.com/ShowSupplierProductsList19141/0.htm

Company Name:	Sinopharm Chemical Reagent Co,Ltd.
Tel:	86-21-63210123
Fax:	86-21-63290778 86-21-63218885
WebSite:	www.reagent.com.cn

Company Name:	S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel:	0755-4000505016 13380397412
Fax:	0755 28094224
WebSite:	http://www.phystandard.com.cn

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