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Andrographolide(5508-58-7)

Andrographolide(5508-58-7)
Product IdentificationBack to Contents
【Product Name】

Andrographolide
【Synonyms】

(3E,4S)-3-[2-[(1S,4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-decalin-1-yl]ethylidene]-4-hydroxy-oxolan-2-one
3-(2-(Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene- 1-naphthalenyl)ethylidene)dihydro-4-hydroxy-, (1R-(1-alpha(E(S*)),4a-beta,5- alpha,6-alpha,8a-alpha))-2(3H)-furanone
Andrographis
【CAS】

5508-58-7
【Formula】

C20H30O5
【Molecular Weight】

350.46
【EINECS】

226-852-5
【RTECS】

LU3490750
【RTECS Class】

Drug; Natural Product
【Merck】

13,638
【Beilstein/Gmelin】

42762
【Beilstein Reference】

4-18-00-02357
Physical and Chemical PropertiesBack to Contents
【Solubility in water】

Insoluble
【Melting Point】

231 - 232
【Boiling Point】

557
【Vapor Pressure】

1E-14 (25 C)
【Density】

1.21 g/cm3
【pKa/pKb】

12.32 (pKa)
【Heat Of Vaporization】

96.4 kJ/mol
【Usage】

May boost immune response.
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water.
【Eyes】

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.
Handling and StorageBack to Contents
【Storage】

Keep tightly closed. Store in a cool dry place.
Hazards IdentificationBack to Contents
【Inhalation】

Material may be irritating to mucous membranes and upper respiratory tract.
【Skin】

May cause skin irritation.
【Eyes】

May cause eye irritation.
【Hazards】

Emits toxic fumes under fire conditions.
【EC Safety Phrase】

22 24/25
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles.
【Respirators】

Government approved respirator.
【Exposure Effects】

The chemical, physical, and toxicological properties of this product have not been thoroughly investigated. Exercise due care.
Fire Fighting MeasuresBack to Contents
【Flash Point】

196
【Fire Fighting】

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Carbon monoxide, Carbon dioxide.
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