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4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester(144701-48-4)

Contents Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Product Identification Back to Contents 【Product Name】 4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester 【Synonyms】 4'-[[4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl]methyl]-2-biphenylcarboxylic acid Micardis 【CAS】 144701-48-4 【Formula】 C33H30N4O2 【Molecular Weight】 514.63 【Merck】 12,10509 Physical and Chemical Properties Back to Contents 【Melting Point】 261-263 【Vapor Pressure】 4.6E-25 (25 C) 【Density】 1.24 g/cm3 【pKa/pKb】 3.83 (pKa) 【Partition Coefficient】 7.73 【Usage】 Angiotensin ii antagonist. First Aid Measures Back to Contents 【Ingestion】 Give 3-4 glasses of water, but DO NOT induce vomiting. If vomiting occurs, give fluids again. Get medical attention to determine whether vomiting or evacuation of stomach is necessary. Do not give anything by mouth to an unconscious or convulsing person. 【Inhalation】 Remove from area to fresh air. Seek medical attention if respiratory irritation develops or if breathing becomes difficult. 【Skin】 Wash affected areas with plenty of water, and soap if available, for several minutes. Seek medical attention if irritation develops or persists. 【Eyes】 Remove contact lenses if necessary. Flush eyes with large amounts of running water for at least 15 minutes. Seek medical attention if irritation develops or persists. Handling and Storage Back to Contents 【Storage】 Store in a cool, dry place (25 C). The bottles should be kept tightly closed. Exposure Controls/Personal Protection Back to Contents 【Personal Protection】 Wear approved respirator and chemically compatible gloves if containers have been compromised and dust is present. 【Exposure Effects】 Possible reaction to dust if inhaled (breathed), ingested (swallowed), or in contact with eyes. The most common adverse events reported were upper respiratory tract infection, back pain, sinusitis, diarrhea and pharyngitis. See Package Insert for further information. The most likely manifestation of overdosage would be hypotension, dizziness, and tachycardia; bradycardia could occur from vagal stimulation. Supportive treatment should be instituted. Telmisartan is not removed by hemodialysis. CHRONIC EXPOSURE: May reduce blood pressure. MEDICAL CONDITIONS POTENTIALLY AGGRAVATED BY EXPOSURE: Dust allergies, and pre-existing respiratory conditions and anyone who is hypersensitive to any component of this product. Persons with low blood volume, and hepatic insufficiency may be at additional risk. Fire Fighting Measures Back to Contents 【Fire Fighting】 Use water spray, foam, CO2, or dry chemical agents to extinguish fires. evacuate personnel to safe area. Firefighters should use self-contained breathing equipment and protective clothing. Use water s pray to keep fire-exposed containers cool. Accidental Release Measures Back to Contents 【Small spills/leaks】 Vacuum or sweep up spillage. Avoid creating dust. Very fine particles can cause a fire or explosion; therefore, eliminate all sources of ignition. Place spillage in appropriate container for waste disposal. Wash contaminated clothing before reuse. Ventilate area, wash down spill site and control wash water. Stability and Reactivity Back to Contents 【Stability】 Stable at normal temperatures and pressures. 【Decomposition】 When heated to decomposition or under fire conditions, material emits oxides of carbon and nitrogen. 【Combustion Products】 Acrid, flammable fumes may develop in a fire.

4'-[[1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl]-methyl]-1,1'-biphenyl-2-carboxylic acid 1,1-dimethylethyl ester(144701-48-4) More Suppliers Company Name: Changzhou Yabang Pharmaceutical Co., Ltd. Tel: 0519-86388158 Fax: WebSite: www.yabangpharma.com Company Name: Beri Pharma Co., Ltd. Tel: 0756-8699456 13427714006 Fax: +86-756-8699456 WebSite: http://www.zhberi.com Company Name: Shouguang Jiasheng Chemical Co., Ltd. Tel: 0536-7971999 13583611556 Fax: 0536-7971999 WebSite: http://jiashengchem.cn/ Company Name: Wuhan DKY Technology Co.,Ltd. Tel: 027-81302411 15377658509 Fax: WebSite: http://www.dkybpc.com/ Company Name: Hubei Chuyunshun Biotechnology Co., Ltd Tel: 15926415536 Fax: WebSite: https://www.chuyunshun.com Company Name: Wuhan Juchengyuan Biotechnology Co., Ltd Tel: 400-027-6007 18062142210 Fax: WebSite: http://www.whjcychem.com Company Name: Zhengzhou Baiyu Pharmaceutical Co., Ltd Tel: 13938569199 Fax: WebSite: Company Name: Ruikangkexin（Hubei）Biotechnology Co., Ltd Tel: 18062078401 Fax: WebSite: