| Product Identification | Back to Contents | 【Product Name】
Amiodarone | 【Synonyms】
(2-Butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diidophenyl)methanone
2-Butyl-3-(3,5-diiodo-4-(beta-diethylaminoethoxy)benzoyl) benzofuran
2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone | 【CAS】
1951-25-3 | 【Formula】
C25H29I2NO3 | 【Molecular Weight】
645.32000000000005 | 【EINECS】
217-772-1 | 【RTECS】
OB1360000 | 【RTECS Class】
Drug; Human Data | 【Merck】
12,504 | 【Beilstein/Gmelin】
1271711 | 【Beilstein Reference】
5-18-02-00353 |
| First Aid Measures | Back to Contents | 【Ingestion】
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Skin】
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
| Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Use NIOSH/MSHA approved respirator appropriate for exposure of concern. | 【Exposure Effects】
with therapeutic use - malaise, fatigue, tremors, lack of coordination, abnormal gait, ataxia, dizziness, and/or paresthesia can occur in up to 4-9% of patients receiving amiodarone. Symmetrical peripheral neuropathy has been described with or without accompanying tremors following doses of 600 to 2000 mg per day. A case report also describes a patient with pseudotumor cerebri thought due to amiodarone. |
| Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. |
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