Product Identification | Back to Contents | 【Product Name】
Demecarium bromide | 【Synonyms】
(m-Hydroxyphenyl)trimethylammonium bromide decamethylenebis[methylcarbamate] Frumtosnil Humorsol Tosmicil Trimethyl-[3-[methyl-[10-[methyl-(3-trimethylazaniumylphenoxy)carbonylamino]decyl]carbamoyl]oxyphenyl]azanium dibromide Visumatic | 【CAS】
56-94-0 | 【Formula】
C32H52Br2N4O4 | 【Molecular Weight】
716.6 | 【EINECS】
200-301-9 | 【RTECS】
BR3130000 | 【RTECS Class】
Other | 【Merck】
12,2936 | 【Beilstein/Gmelin】
3880925 | 【Beilstein Reference】
4-13-00-00968 |
First Aid Measures | Back to Contents | 【Ingestion】
Induction of vomiting is usually not necessary due to spontaneous vomiting. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Bethanechol - for substantial ingestions of bethanechol, consider gastric lavage preceded by endotracheal intubation. Other agents - carbachol, acetylcholine, and pilocarpine are liquids, rapidly absorbed and probably not removed significantly by gastric emptying procedures. Atropine sulfate is the drug of choice. For significant muscarinic symptoms administer: adults - 2 to 4 mg iv, repeated every 3 to 60 minutes as needed to control symptoms, then prn for 24 to 48 hours. Child - 0.04 To 0.08 Mg/kg iv (up to 4 mg) repeated every 5 to 60 minutes as necessary. Epinephrine - may assist in overcoming severe cardiovascular or bronchoconstrictor responses (dose: 0.1 To 1.0 Mg sc). | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Skin】
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. | 【Eyes】
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. |
Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
Hazards Identification | Back to Contents | 【Ingestion】
Nausea, vomiting, abdominal pain, diarrhea, or belching may be noted. | 【Inhalation】
Dyspnea, bronchospasm, tachypnea, increased bronchial secretions, and pulmonary edema may occur, especially in asthmatic patients. |
Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Use NIOSH/MSHA approved respirator appropriate for exposure of concern. |
Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. |
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AN PharmaTech Co Ltd |
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