18-beta-Glycyrrhetinic acid(471-53-4)

Contents

Product Identification	Back to Contents
【Product Name】 18-beta-Glycyrrhetinic acid
【Synonyms】 Arthrodont Enoxolone Glycyrrhetin Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3b,20b)- Subglycyrrhelinic acid Uralenic acid
【CAS】 471-53-4
【Formula】 C30H46O4
【Molecular Weight】 470.69
【EINECS】 207-444-6
【RTECS】 RK0180000
【RTECS Class】 Other
【Merck】 12,3628
【Beilstein/Gmelin】 2229654
【Beilstein Reference】 4-10-00-03775

Physical and Chemical Properties	Back to Contents
【Appearance】 White to gray white solid.
【Solubility in water】 Insoluble
【Melting Point】 327 - 330
【pKa/pKb】 4.71 (pKa)
【Usage】 Expectorant and antitussive.

First Aid Measures	Back to Contents
【Ingestion】 Get medical aid. Wash mouth out with water.
【Inhalation】 Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】 Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】 Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage	Back to Contents
【Storage】 Store in a cool, dry place. Store in a tightly closed container. Refrigerator (approx 4 C).
【Handling】 Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification	Back to Contents
【Ingestion】 May cause irritation of the digestive tract. May be harmful if swallowed.
【Inhalation】 May cause respiratory tract irritation. May be harmful if inhaled.
【Skin】 May cause skin irritation. May be harmful if absorbed through the skin.
【Eyes】 May cause eye irritation.

Exposure Controls/Personal Protection	Back to Contents
【Personal Protection】 Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】 Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Poison Class】 4

Fire Fighting Measures	Back to Contents
【Fire Fighting】 Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures	Back to Contents
【Small spills/leaks】 Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity	Back to Contents
【Stability】 Stable under normal temperatures and pressures.
【Incompatibilities】 Strong acids, strong bases, oxygen.
【Decomposition】 Carbon monoxide, carbon dioxide.

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