Diflunisal(22494-42-4)

Contents

Product Identification	Back to Contents
【Product Name】 Diflunisal
【Synonyms】 5-(2,4-Difluorophenyl)-2-hydroxybenzoic acid 5-(2,4-Difluorophenyl)salicylic acid Fluodonil
【CAS】 22494-42-4
【Formula】 C13H8F2O3
【Molecular Weight】 250.2
【EINECS】 245-034-9
【RTECS】 DV2030000
【RTECS Class】 Drug; Mutagen; Reproductive Effector; Human Data
【Merck】 12,3190
【Beilstein/Gmelin】 2654431
【Beilstein Reference】 6-10

Physical and Chemical Properties	Back to Contents
【Solubility in water】 Slightly soluble
【Melting Point】 210 - 211
【Boiling Point】 390
【Vapor Pressure】 1E-6 (25 C)
【pKa/pKb】 2.94 (pKa)
【Partition Coefficient】 4.24
【Heat Of Vaporization】 67.1 kJ/mol
【Usage】 Antiinflammatory drug.

First Aid Measures	Back to Contents
【Ingestion】 If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Inhalation】 If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
【Skin】 In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
【Eyes】 In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage	Back to Contents
【Storage】 Keep tightly closed. Store in a cool dry place.

Hazards Identification	Back to Contents
【Inhalation】 May be harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.
【Skin】 May be harmful if absorbed through the skin.
【Ingestion】 Harmful if swallowed.
【Hazards】 Emits toxic fumes under fire conditions.
【EC Risk Phrase】 22 36/37/38 63
【EC Safety Phrase】 22 26 36

Exposure Controls/Personal Protection	Back to Contents
【Personal Protection】 Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
【Exposure Effects】 Harmful if swallowed. Irritating to eyes, respiratory system and skin. Possible risk of harm to the unborn child. Possible sensitizer. Target organ(s): Blood. Liver.

Fire Fighting Measures	Back to Contents
【Flash Point】 188
【Fire Fighting】 Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures	Back to Contents
【Small spills/leaks】 Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity	Back to Contents
【Stability】 Stable at normal temperatures and pressures.
【Decomposition】 Carbon monoxide, Carbon dioxide, Hydrogen fluoride.

Company Name:	Hubei Chenxin Pharmaceutical Co., Ltd.
Tel:	17362916295 17362916295
Fax:	QQ:840947394
WebSite:	http://www.chenxinyaoye.cn

Company Name:	Wuhan DingCheng Biochemical Co.Ltd
Tel:	13545255233 13545255233
Fax:
WebSite:	www.whdcsk.com/index.htm

Company Name:	Chemsky（shanghai）International Co.,Ltd.
Tel:	021-50135380
Fax:
WebSite:	www.shchemsky.com

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