10（11）-EpDPA

中文名称

10（11）-EpDPA

英文名字

10(11)-EpDPA

供应商

开曼生物

产品货号

10471-25

产品报价

￥539/25ug

产品说明书

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产品新闻

背景资料

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. 10(11)-EpDPA is a docosahexaenoic acid (DHA; Item No. 90310) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 µM.{29509,29508} 10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.{29509,26641}

产品描述

A DHA epoxygenase metabolite detected in rat brain and spinal cord, as well as human serum, that acts as a substrate for sEH (Km = 5.1 µM); demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models and potently inhibits angiogenesis and tumor growth in in vitro assays

保存建议

建议您在收到开曼生物品牌的10,11 EDP; 10,11-epoxy Docosapentaenoic Acid; 10(11)-EpDPE; 10,11-epoxy DPA (CAS 895127-65-8) (25 ug)产品后置于-20℃保存.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体.作为开曼生物在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的开曼生物产品以及客户订制化服务.