Description: Ald-CH2-PEG5-azide is a crosslinker containing an azide group and an aldehyde group. The azide group enables PEGylation via Click Chemistry. The aldehyde group reacts with amines and the N-terminal of peptides and proteins to form an imine containing a C=N double bond, which can be further reduced. PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage.
Name: Ald-CH2-PEG5-azide
CAS#: 1446282-38-7
Chemical Formula: C12H23N3O6
Exact Mass: 305.1587
Molecular Weight: 305.33
Elemental Analysis: C, 47.21; H, 7.59; N, 13.76; O, 31.44
Synonym: Ald-CH2-PEG5-azide
IUPAC/Chemical Name: 17-azido-3,6,9,12,15-pentaoxaheptadecanal
InChi Key: VYTIEPBAXZXQJS-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H23N3O6/c13-15-14-1-3-17-5-7-19-9-11-21-12-10-20-8-6-18-4-2-16/h2H,1,3-12H2
SMILES Code: [H]C(COCCOCCOCCOCCOCCN=[N+]=[N-])=O
Appearance: Solid powder
Purity: >95% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
关键字： 1446282-38-7;PEG5-azide;
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