2S-氨基-1-（磷酸二氢）-4E-十八烯-1，3R-二醇

中文名称

2S-氨基-1-（磷酸二氢）-4E-十八烯-1，3R-二醇； S1P |鞘氨醇-1-磷酸；鞘氨醇-1-磷酸

英文名字

2S-amino-1-（dihydrogen phosphate）-4E-octadecene-1，3R-diol； S1P|Sphingosine-1-Phosphoric Acid； Sphingosine-1-Phosphate

供应商

开曼生物

产品货号

62570-10

背景资料

Sphingosine-1-phosphate （S1P） is the product of phosphorylation of sphingosine by sphingosine kinase. Like many products of sphingomyelin， it exhibits a wide range of biological activities. Not only does it enhance cell growth， but it can inhibit the normal apoptotic response to a variety of stimuli. The ability of PKC to block apoptosis is likely due to the formation of S1P. S1P stimulates MAPK and counteracts the ceramide-induced activation of SAPK and JNK. It also increases intracellular calcium levels by both the liberation of calcium from internal stores and through activation of a Gi protein-coupled receptor resulting in the opening of a cell surface calcium channel.

产品描述

A potent lipid signaling molecule that exhibits a wide range of biological activities； it enhances cell growth and inhibits the normal apoptotic response to a variety of stimuli

保存建议

建议您在收到开曼生物品牌的Sphingosine-1-Phosphate （10 mg）产品后置于-20度保存，产品有效期为365天.

其他

开曼生物向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒，其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域.开曼生物可提供用于检测的特色试剂盒，如：类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等；也提供多种高质量试剂，包括：类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体 .