Product Name:Bulevirtide
CAS No.:2012558-47-1
Synonyms:Myrcludex B;布尔韦肽
Catalog No.:218P060
Brand:HongTide(上海鸿肽生物)
Description:Bulevirtide是一种用于治疗慢性丁型肝炎(存在乙型肝炎)的抗病毒药物,序列中含有48个氨基酸,其中包含一个肉豆蔻酸。最常见的副作用包括血液中胆盐水平升高和注射部位反应。Bulevirtide的作用是附着并阻断受体(靶标),δ型肝炎病毒和乙型肝炎病毒通过该受体(靶标)进入肝细胞。通过阻止病毒进入细胞,它限制了HDV(丁型肝炎病毒)的复制能力及其在体内的影响,从而减轻了疾病的症状Bulevirtide于 2020 年7月在欧盟获批用于医疗用途。
Bulevirtide is an antiviral drug used to treat chronic hepatitis D (where hepatitis B is present). The sequence contains 48 amino acids, including a myristic acid. The most common side effects include elevated bile salt levels in the blood and injection site reactions. The role of Blevirtide is to attach and block receptors (targets), δ Hepatitis B virus and hepatitis B virus enter hepatocytes through this receptor (target). By preventing the virus from entering cells, it limits the replication ability of HDV (hepatitis D virus) and its impact in the body, thereby alleviating the symptoms of the disease. Bulevirtide was approved for medical use in the European Union in July 2020.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Myr-GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANKVG-NH2 |
Sequence(3-letter code) | Myr-Gly-Thr-Asn-Leu-Ser-Val-Pro-Asn-Pro-Leu-Gly-Phe-Phe-Pro-Asp-His-Gln-Leu-Asp-Pro-Ala-Phe-Gly-Ala-Asn-Ser-Asn- Asn-Pro-Asp-Trp-Asp-Phe-Asn-Pro-Asn-Lys-Asp-His-Trp-Pro-Glu-Ala-Asn-Lys-Val-Gly-NH2 |
Peptide Structure | 
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Molecular Formula | C248H355N65O72 |
Molecular Weight |
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邮箱:sales1@hongtide.com
关键字: 2012558-47-1;Bulevirtide;布尔韦肽;Myrcludex B;多肽;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。