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Description
Aducanumab (brand name: Aduhelm) is an amyloid beta-directed monoclonal antibody that targets amyloid beta in the brains of people with Alzheimer’s to reduce its buildup. Aducanumab is a monoclonal antibody (a protein that helps your immune system target other proteins), and it is designed to help your body remove something called amyloid beta from the brain. Amyloid beta is an important protein involved in the progression of Alzheimer’s disease. Aducanumab is given intravenously (infused through a vein) monthly. Aducanumab does not cure Alzheimer’s disease, but one (of two) large clinical studies suggests that aducanumab may slow the progression of the earliest symptoms of Alzheimer’s disease.
Catalog No.
DHC12504
Host species
Homo sapiens
Species reactivity
Human
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Concentration
2.13 mg/ml
Purity
>95%
Clonality
Monoclonal
Isotype
IgG1-kappa
Applications
Research Grade Biosimilar
Target
AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50
Purification
Protein A or G purified from cell culture supernatant.
Endotoxin level
Please contact with the lab for this information.
Expression system
XtenCHO
Accession
P05067
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
Alternative Names
BART, BIIB-037, CAS: 1384260-65-4
Note
For research use only. Not suitable for clinical or therapeutic use.
关键字: Aducanumab;阿度努单抗;1384260-65-4;AICD-57, A4;APP, Abeta40;
武汉佰乐博生物(Biolab Reagents)创立于 2021 年,核心创始团队由五位毕业于武汉大学、华中科技大学、华中农业大学等知名高校的生命科学领域顶级研究者组成,团队均拥有二十年行业深耕经验,积淀了丰富的产品开发与技术应用能力。
佰乐博生物是国家高新技术企业、国家科技型中小企业,并已通过ISO9001 质量管理体系、ISO13485 医疗器械质量管理体系双认证,以标准化品控体系筑牢产品品质根基。公司依托全球领先的技术平台,专注于全球高品质生物试剂的引进与整合,同时作为法国 AntibodySystem 品牌亚洲独家总代理,构建起近 30000 种生命科学试剂的丰富产品矩阵,核心产品涵盖蛋白、抗体、试剂盒三大品类,全维度满足科研实验多元需求。
自成立以来,佰乐博生物始终致力于为广大生命科学科研工作者提供专业、全面、可靠的试剂产品与技术支持,以优质科研工具助力科研探索,推动生命科学研究的深入发展。