Tags:Varlilumab 代理商,Varlilumab 价格,Varlilumab 供应商， Varlilumab supplier,Varlilumab purchase,Varlilumab 购买,Varlilumab 销售
Description
Varlilumab is a fully human monoclonal antibody (mAb) that targets CD27, a critical molecule in the activation pathway of lymphocytes. Like CD40, CD27 can be effectively manipulated with activating antibodies to induce potent anti-tumor responses, and may result in less toxicities due to its restricted expression and regulation. Varlilumab is a novel, first-in-class, agonist CD27 antibody that stimulates the CD27 pathway, which results in T-cell activation and antitumor activity in tumor models. This first-in-human, dose-escalation and expansion study evaluated the safety, pharmacology, and activity of varlilumab in patients with advanced solid tumors.
Catalog No.
DHD72201
Host species
Homo sapiens
Species reactivity
Human
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Concentration
0.63 mg/ml
Purity
>95%
Clonality
Monoclonal
Isotype
IgG1-kappa
Applications
Research Grade Biosimilar
Target
CD27L receptor, TNFRSF7, T14, CD27 antigen, Tumor necrosis factor receptor superfamily member 7, CD27, T-cell activation antigen CD27
Purification
Protein A or G purified from cell culture supernatant.
Endotoxin level
Please contact with the lab for this information.
Expression system
XtenCHO
Accession
P26842
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
Alternative Names
1F5, CDX-1127, CAS: 1393344-72-3
Note
For research use only. Not suitable for clinical or therapeutic use.
关键字： Varlilumab;伐立鲁单抗;1393344-72-3;TNFRSF7, T14;CD27;
武汉佰乐博生物（Biolab Reagents）由五位毕业于华中科技大学，华中农业大学，武汉大学等知名高校，且具有二十年工作经验的生命科学领域顶级研究者创立于2021年，凭借丰富的产品开发经验，利用全球领先的技术平台，引进和整合全球高品质的蛋白、抗体和试剂盒产品。目前，佰乐博生物作为法国AntibodySystem在亚洲的独家总代理，提供近30,000种生命科学试剂，核心产品涵盖蛋白、抗体和试剂盒，旨在为科研工作者提供专业、全面、可靠的试剂支持，推动生命科学研究的深入发展。