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Description
ANB020, now called etokimab, is currently in phase 2a testing in eczema, which is also known as atopic dermatitis. Scientists from the Medical Research Council Human Immunology Unit at the University of Oxford released data from 12 patients showing that 83% who were treated with etokimab reported a reduction in disease severity after 29 days. Etokimab, an anti-IL-33 biologic, has previously demonstrated a good safety profile and favorable pharmacodynamic properties in many clinical studies. Etokimab is designed to block interleukin-33 (IL-33), an immune-signaling molecule. In peanut allergy, the body overreacts to peanuts as IL-33 activates an antibody called immunoglobin E. These antibodies cause allergic response such as mouth itchiness, hives, breathing difficulties and potentially fatal anaphylactic shock.
Catalog No.
DHB74001
Host species
Humanized
Species reactivity
Human
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Concentration
1 mg/ml
Purity
>95%
Clonality
Monoclonal
Isotype
IgG1-kappa
Applications
Research Grade Biosimilar
Target
NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11
Purification
Protein A or G purified from cell culture supernatant.
Endotoxin level
Please contact with the lab for this information.
Expression system
XtenCHO
Accession
O95760
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
Alternative Names
ANB020, CAS: 2022981-44-6,IL33
Note
For research use only. Not suitable for clinical or therapeutic use.
关键字： Etokimab;艾托奇单抗;2022981-44-6;NF-HEV, IL-1F11;C9orf26, IL-33;
武汉佰乐博生物（Biolab Reagents）始创于 2021 年，核心创始团队由五位毕业于武汉大学、华中科技大学、华中农业大学等高校的生命科学领域顶尖研究者组成，团队深耕行业二十载，积淀了扎实的产品开发实力与技术应用经验，筑牢企业核心技术根基。
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自成立以来，佰乐博生物始终为科研工作者、生物医药工业客户提供专业的产品与技术支持，以优质科研工具赋能科研，助力生命科学研究创新发展、深度突破。