2-Deoxy-D-Ribose is a naturally occurring monosaccharide and a crucial structural component of DNA. Unlike regular D-ribose, which has a hydroxyl group (-OH) on the 2' carbon, 2-deoxy-D-ribose lacks this hydroxyl group, making it a “deoxy” sugar. Its molecular formula is C₅H₁₀O₄.
This sugar plays a central biological role as part of the backbone of deoxyribonucleic acid (DNA), where it alternates with phosphate groups to form the DNA strand structure. The absence of the hydroxyl group at the 2' position increases DNA’s chemical stability compared to RNA, which contains D-ribose.
Beyond its genetic function, 2-deoxy-D-ribose is also used in biochemical research, including studies related to oxidative stress, apoptosis, and cancer metabolism. Some research suggests it may be involved in cellular oxidative damage and can serve as a pro-oxidant agent in certain experimental models.
Commercially, 2-deoxy-D-ribose is available as a fine chemical used in laboratory applications, particularly in assays involving DNA damage or antioxidant testing. Its unique chemical structure makes it valuable in nucleoside synthesis and other molecular biology applications.
关键字： 2-Deoxy-D-Ribose;
武汉恒和达生物医药有限公司成立于2013年，公司总部位于武汉经济技术开发区民营科技工业园，为湖北省高新技术企业，主要从事原料药、高端医药中间体和精细化工产品的研发与生产，以及新化合物的技术咨询和检测等服务。恒和达生物目前拥有1000平米的研发及中试平台，并配备了各种现代化的实验研究设备，满足了各种化合物的小试研究，中试放大的生产。合作生产基地占地30余亩，配备了成套大型不锈钢和搪玻璃生产设备，反应釜设备从50L到2000L不等，具有吨位级的研发生产能力。