Rabbit Anti-EIF2S1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:EIF2S1
IR:Immunogen Range:75-180/315
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1965
Swiss Prot:P05198
Source:KLH conjugated synthetic peptide derived from human eIF2 alpha:75-180/315
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:eIF2 alpha is a 36 kDa protein which is ubiquitously expressed in many cell types. The eIF2 protein, which is composed of three subunits (alpha, beta and gamma), is one of the key molecules in the initiation of translation. In mammalian cells, eIF2 alpha is phosphorylated at serine 51 (human EIF2 alpha, the equivalent residue in mouse is serine 52) by at least two kinases: the haem-controlled repressor (HCR) and the interferon inducible double stranded RNA-dependent protein kinase (PKR). Phosphorylation of eIF2 alpha blocks the GDP-GTP exchange activity of eIF2 beta, resulting in the suppression of protein synthesis. The phosphorylation of eIF2 alpha is an important regulatory process in protein synthesis.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:200-800)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Cow
Rabbit
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： EIF2S1;EIF2A;CDA 02;CDA02;EIF-2alpha;EIF2;EIF2alpha;eIF2S1;
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