Rabbit Anti-AKT3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:AKT3
IR:Immunogen Range:101-200/479
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10000
Swiss Prot:Q9Y243
Source:KLH conjugated synthetic peptide derived from human AKT3:101-200/479
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphtidylinositol 3 kinase (PI 3 kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). IGF1 leads to the activation of AKT3, which may play a role in regulating cell survival. It is capable of phosphorylating several known proteins.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:200-600)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Horse
Rabbit
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： AKT3;AKT3 kinase;DKFZP434N0250;PKB Gamma;PKBG;PRKBG;Protein Kinase AKT3;AKT3_HUMAN;
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