Rabbit Anti-SPON1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:SPON1
IR:Immunogen Range:741-807/807
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10418
Swiss Prot:Q9HCB6
Source:KLH conjugated synthetic peptide derived from human SPON1/F spondin:741-807/807
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:SPON1 is a member of a subgroup of the thrombospondin type 1 (TSR) class molecules, defined by two domains of homology, the FS1/FS2 and TSR domains. The TSRs of SPON1 proteins are typical of class 2 TSRs. SPON1, which is similar to thrombospondin, is a extracellular matrix attached molecule that promotes neurite outgrowth and inhibits angiogenesis. Analysis of gain and loss of function experiments reveal that SPON1 is required for accurate pathfinding of embryonic axons, and plays a dual role in patterning axonal trajectories. It promotes the outgrowth of commissural and inhibits the outgrowth of motor axons, and has also been implicated in inflammatory processes in the nervous system.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： SPON1;F spondin;FSPO;KIAA0762;MGC10724;SPON 1;Spondin1;SPON1_HUMAN;
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