Rabbit Anti-phospho-CD130/gp130 (Ser782) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-CD130/gp130 (Ser782)
IR:Immunogen Range:SE(p-S)TQ
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3572
Swiss Prot:P40189
Source:KLH conjugated Synthesised phosphopeptide derived from human gp130 around the phosphorylation site of Ser 782:SE(p-S)TQ
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： phospho-CD130/gp130 ;gp130 (phospho S782);gp130 (phospho Ser78;p-gp130 (Ser782);Interleukin-6 recept;IL-6R-beta;CDw130;IL6RB_HUMAN;
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