Rabbit Anti-ERO1LB Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ERO1LB
IR:Immunogen Range:1-100/467
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:56605
Swiss Prot:Q86YB8
Source:KLH conjugated synthetic peptide derived from human ERO1LB:1-100/467
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Rabbit
Guinea Pig
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： ERO1LB;Endoplasmic ;oxidoreductin;oxidoreductin-1-like;ERO1-L-beta;ERO1-like protein be;Oxidoreductin-1-L-be;ERO1B_HUMAN;
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