Rabbit Anti-IL-7 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:IL-7
IR:Immunogen Range:51-154/154
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:16196
Swiss Prot:P10168
Source:KLH conjugated synthetic peptide derived from mouse IL-7:51-154/154
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Interleukin 7 (IL7) is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL7 stimulates the proliferation of CD4+/CD8+ cells. The proliferative response of thymocytes to IL7 is not affected by antibodies to the T cell growth factors such as IL2, IL4 and IL6, suggesting that IL7 is capable of stimulating T cell proliferation through a pathway independent of the known T cell growth factors. Mature T cells respond to IL7 and Con A, but not to IL7 alone. In myeloid lineage cells, IL7 upregulates the production of pro-inflammatory cytokines and stimulates the tumoricidal activity of monocytes/macrophages. IL7 is expressed by adherent stromal cells from various tissues.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： IL-7;Interleukin-7;Interleukin7;IL7;IL 7;IL7_HUMAN;IL7_MOUSE;LP-1;
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