Rabbit Anti-NPHS2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:NPHS2
IR:Immunogen Range:231-330/383
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7827
Swiss Prot:Q9NP85
Source:KLH conjugated synthetic peptide derived from human NPHS2/Podocin:231-330/383
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： NPHS2;nephrosis 2;idiopathic; steroid resistant;NPHS2 gene;PDCN;Podocin;PODO_HUMAN;
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