Rabbit Anti-BHLHE41 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:BHLHE41
IR:Immunogen Range:21-120/482
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:79365
Swiss Prot:Q9C0J9
Source:KLH conjugated synthetic peptide derived from human SHARP1/DEC2:21-120/482
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:DEC1 is a 412 amino acid, basic helix-loop-helix (bHLH) containing protein that is involved in the control of proliferation and/or differentiation of several cell types including nerve cells, fibroblasts and chondrocytes. The bHLH region of DEC1 is structurally similar to the bHLH regions of the mammalian HES family, Drosophila hairy and Drosophila Enhancer of split m7. DEC1 is a novel direct target for cAMP in a wide range of cells, and is involved in the control of gene expression in cAMP-activated cells. DEC2, also known as SHARP1, is highly expressed in skeletal muscle and brain. The gene encoding human DEC2 maps to chromosome 12p11.23-p12.1. DEC1 and DEC2 play a role in regulating the mammalian molecular clock by suppressing the transcription of specific clock genes. Both DEC1 and DEC2 are detected in the suprachiasmimc nucleus in a circadian fashion. Brief light impulses induce the expression of DEC1 in a phase-dependent manner.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： BHLHE41;SHARP-1;BHLHB3;DEC2;SHARP1;BHLH3; bHLH protein DEC2;BHE41_HUMAN;
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