Rabbit Anti-PMCA2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:PMCA2
IR:Immunogen Range:361-460/1243
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:491
Swiss Prot:Q01814
Source:KLH conjugated synthetic peptide derived from human PMCA:361-460/1243
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Plasma membrane-type Ca2+-ATPases (PMCAs) mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from at least four distinct genes. The expression of different PMCA isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, and with respect to the physiological needs of specific cell and tissue types. Spatial and temporal rates of resting intracellular Ca2+ concentrations and Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： PMCA2;ATP2B1;ATP2B2;ATP2B3;ATP2B4;PMCA2;PMCA3;AT2B2_HUMAN;
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