Rabbit Anti-CTRP5 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CTRP5
IR:Immunogen Range:191-243/243
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:114902
Swiss Prot:Q9BXJ0
Source:KLH conjugated synthetic peptide derived from human CTRP5:191-243/243
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Members of the C1q superfamily have diverse functions that are related to cell adhesion and basement membrane components. CTRP5 (Complement C1q tumor necrosis factor-related protein 5) is a 243 amino acid secreted and membrane-associated protein that contains a collagen-like domain and a C1q domain. CTRP5 is a short-chain collagen that is expressed in retinal pigment epithelium as well as brain, lung, liver and placenta. By forming an extracellular hexagonal lattice, CTRP5 facilitates the adhesion of basal retinal pigment epithelium to Bruch’s membrane, the innermost layer of the choroid. A mutation within the C1q domain of CTRP5 results in abnormal high molecular weight aggregate formation, which alters its structure and interactions. This mutation may result in the presentation of late-onset retinal degeneration (LORD), an autosomal dominant disorder that is characterized by punctate yellow-white deposits in the retinal fundus and night blindness.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： CTRP5;C1q and tumor necros;C1QTNF5;Complement C1q ;LORD;CTRP5补体C1q和肿瘤坏死因子相关蛋;补体C1q和肿瘤坏死因子相关蛋白5抗体;C1QT5_HUMAN;
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