Rabbit Anti-Fragilis Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Fragilis
IR:Immunogen Range:41-100/133
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10410
Swiss Prot:Q01628
Source:KLH conjugated synthetic peptide derived from human Fragilis/IP15:41-100/133
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:IFITM3 is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins. IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes. Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis. Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-?and IFN-? IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： Fragilis;1 8U;Ifitm 3;IFITM3;Interferon inducible;IP15;干扰素诱导跨膜蛋白3抗体;IFM3_HUMAN;
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