Rabbit Anti-CATSPER3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CATSPER3
IR:Immunogen Range:201-300/398
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:347732
Swiss Prot:Q86XQ3
Source:KLH conjugated synthetic peptide derived from human CATSPER3:201-300/398
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： CATSPER3;putative ion channel;CATSPER3;CACRC;Ca(v)-like protein;CACRC;putative ion channel;CTSR3_HUMAN;
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