Mouse Anti-ATG5/APG5L Monoclonal Antibody
DATASHEET
Host:Mouse
Target Protein:ATG5/APG5L
IR:Immunogen Range:full length
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:9474
Swiss Prot:Q9H1Y0
Source:Recombinant human ATG5 Protein:full length
Purification:affinity purified by Protein G
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:In yeast, autophagy is an essential process for survival during nutrient starvation and cell differentiation. The process of autophagy is characterized as a non-selective degradation of cytoplasmic proteins into membrane stuctures called autophagosomes, and it is dependent on several proteins, including the autophagy proteins APG5 and APG7. Yeast Apg7 and the human homolog, APG7, share similarities with the ubiquitin-activating enzyme E1 in Saccharomyces cerevisiae and are likewise responsible for enzymatically activating the autophagy conjugation system. Apg5 and the human homolog, APG5 (also designated apoptosis-specific protein or APS), function as substrates for the autophagy protein Apg12. These proteins are covalently bonded together to form Apg12/APG5 conjugates, which are required for the progression of autophagy.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： ATG5/APG5L;APG5L;ATG5;APG5 like;APG5L;ATG5;hAPG5;ATG5_HUMAN;
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